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T = 0, all patients were in S1 , the active disease state; and all transitions are interval-censored due to the intermittent observation pattern of clinic visits. For simplicity, we assume that the interval censoring and any right censoring due to mortality are noninformative in this illustrative example. Preliminary analyses indicated that the assumption of constant baseline transition rates over
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Below. The ICSR data were normalised to take into account the length of time a country has been in the PIDM, as well as the population size, by expressing the ICSRs as number of reports per million person-years. In order to know the main product classes implicated in ICSRs, all products reported as suspected of causing a reaction were aggregated on the fourth-level ATC code, and the number of time
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D more self-directed, independent education resources; for example, I've read several books about this. . . [FG2,M2] And, Whenever I need some information, I go to all the Internet sites. The Internet. . . gives me very good material. So with that I manage myself. [I,M8]. Even when men used more social information sources, they combined them with independent information seeking: I went to the Hosp
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D more self-directed, independent education resources; for example, I've read several books about this. . . [FG2,M2] And, Whenever I need some information, I go to all the Internet sites. The Internet. . . gives me very good material. So with that I manage myself. [I,M8]. Even when men used more social information sources, they combined them with independent information seeking: I went to the Hosp
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Addition, the R220 seems to play a central role in -lactamase inhibition/inactivation. Thus, the R220K mutant was relatively "inhibitor susceptible", being not capable anymore to hydrolyze clavulanic acid as compared to KPC-2. On the other hand, the R220M mutant demonstrated increased Km values for -lactamase inhibitors, which resulted in inhibitor resistance [139]. Mutagenesis of residue Glu276 i
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Of the environment limit the ability to take individual action in response to what is learned. This was evidenced by the failure of the SATZ Cape Town intervention to impact on adolescent risk behavior in Cape Town. Therefore the Western Cape PREPARE project aims to change the school environment in two aspects. Firstly, we aim to increase adolescent access to sexual- and reproductive health servic
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Case of Ms A was concurrent with the discontinuation of antidepressants. This onset contrasts with what has been reported in the literature, wherein the tinnitus onset has been associated with the commencement of an antidepressant and cessation of the antidepressant has been followed by cessation of the tinnitus (except for the authors of 1 article who found that tinnitus was associated with withd
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Case of Ms A was concurrent with the discontinuation of antidepressants. This onset contrasts with what has been reported in the literature, wherein the tinnitus onset has been associated with the commencement of an antidepressant and cessation of the antidepressant has been followed by cessation of the tinnitus (except for the authors of 1 article who found that tinnitus was associated with withd